Premium
Front cover story: Eur. J. Immunol. 12'20
Publication year - 2020
Publication title -
european journal of immunology
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 2.272
H-Index - 201
eISSN - 1521-4141
pISSN - 0014-2980
DOI - 10.1002/eji.202070120
Subject(s) - front cover , cover (algebra) , biology , citation , cd8 , pathology , head and neck , immune system , immunology , library science , medicine , computer science , surgery , mechanical engineering , engineering
This cover features a colorful interpretation of figure 4D, which is taken from Panigrahi et al. (pp. 2055–2066). The image portrays CD8 + (blue)CD73 + (green) cells in tumour tissue that was prepared from squamous cell carcinoma of a 70 year old male. The tissue section was stained using Tyramide‐Cy3‐based labelling and visualized with immunofluorescence microscopy. The observation provides direct evidence that these cells gain close proximity to tumour cells, and consequently, may contribute to immune suppression in head and neck tumour microenvironments. The original image was digitally modified for the cover.