Premium Induction of diverse T cell memory through antibody‐mediated activation in micePremium
Author(s)
Taylor Matthew D.,
Brewer Mariana R.,
Deutschman Clifford S.
Publication year2020
Publication title
european journal of immunology
Resource typeJournals
PublisherWiley-Blackwell
Recent studies have demonstrated that laboratory mice lack a robust repertoire of memory T cell. Administration of an anti‐CD3ε activating antibody (clone 145‐2C11) induces persistent CD4 and CD8 T cell memory in both lymphatic and solid organs while maintaining T cell responses and without increased anergy or altering innate immunity.
Subject(s)acoustics , antibody , biology , cd8 , cell , clone (java method) , gene , genetics , immune system , immunity , immunological memory , immunology , lymphatic system , memory cell , memory t cell , microbiology and biotechnology , physics , quantum mechanics , repertoire , t cell , transistor , voltage
Language(s)English
SCImago Journal Rank2.272
H-Index201
eISSN1521-4141
pISSN0014-2980
DOI10.1002/eji.202048570
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