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ESC Working Group on Myocardial Function Position Paper: how to study the right ventricle in experimental models
Author(s) -
LeiteMoreira Adelino F.,
Lourenço André P.,
Balligand JeanLuc,
Bauersachs Johann,
Clerk Angela,
De Windt Leon J.,
Heymans Stephane,
HilfikerKleiner Denise,
Hirsch Emilio,
Iaccarino Guido,
Kaminski Karol A.,
Knöll Ralph,
Mayr Manuel,
Tarone Guido,
Thum Thomas,
Tocchetti Carlo G.
Publication year - 2014
Publication title -
european journal of heart failure
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.149
H-Index - 133
eISSN - 1879-0844
pISSN - 1388-9842
DOI - 10.1002/ejhf.66
Subject(s) - ventricle , medicine , position (finance) , hemodynamics , cardiology , position paper , cardiac function curve , set (abstract data type) , heart failure , pathology , computer science , finance , economics , programming language
The right ventricle has become an increasing focus in cardiovascular research. In this position paper, we give a brief overview of the specific pathophysiological features of the right ventricle, with particular emphasis on functional and molecular modifications as well as therapeutic strategies in chronic overload, highlighting the differences from the left ventricle. Importantly, we put together recommendations on promising topics of research in the field, experimental study design, and functional evaluation of the right ventricle in experimental models, from non‐invasive methodologies to haemodynamic evaluation and ex vivo set‐ups.