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State of the Art: Newer biomarkers in heart failure
Author(s) -
de Boer Rudolf A.,
Daniels Lori B.,
Maisel Alan S.,
Januzzi James L.
Publication year - 2015
Publication title -
european journal of heart failure
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.149
H-Index - 133
eISSN - 1879-0844
pISSN - 1388-9842
DOI - 10.1002/ejhf.273
Subject(s) - medicine , heart failure , intensive care medicine , procalcitonin , disease , natriuretic peptide , clinical practice , troponin , management of heart failure , cardiology , sepsis , myocardial infarction , physical therapy
Since natriuretic peptides were successfully integrated into the clinical practice of heart failure ( HF ), the possibility of using new biomarkers to advance the management of affected patients has been explored. While a huge number of candidate HF biomarkers have been described recently, very few have made the difficult translation from initial promise to clinical application. These markers mirror the complex pathophysiology of heart failure at various levels: cell loss (troponin), fibrosis ( ST2 and galectin‐3), infection (procalcitonin), and renal disease (several renal markers). In this review, we examine the best emerging candidates for clinical assessment and management of patients with HF .