
Risk of mortality among inpatients with COVID‐19 and type 2 diabetes: National data from Kuwait
Author(s) -
AlOzairi Ebaa,
Brown Rosemary,
Hamdan Yasmine,
Alabdullah Lulwa,
Voase Nia,
Al Kandari Jumana,
Alsaeed Dalal,
Al Ozairi Abdulla,
Hasan Amal,
AlMulla Fahd,
Katikireddi Srinivasa Vittal,
Gray Stuart R.,
Gill Jason M. R.,
CelisMorales Carlos A.,
Sattar Naveed,
Welsh Paul
Publication year - 2021
Publication title -
endocrinology, diabetes and metabolism
Language(s) - English
Resource type - Journals
ISSN - 2398-9238
DOI - 10.1002/edm2.287
Subject(s) - medicine , diabetes mellitus , type 2 diabetes , population , logistic regression , retrospective cohort study , risk factor , attributable risk , pediatrics , demography , epidemiology , environmental health , endocrinology , sociology
To investigate type 2 diabetes as a risk factor for COVID‐19 death following hospital admission in Kuwait. Methods A retrospective cohort study using data from a central hospital that cared for all hospitalized COVID‐19 patients in Kuwait. We investigated the association between type 2 diabetes, with COVID‐19 mortality using multiply imputed logistic regression and calculated the population attributable fraction. Results A total of 5333 patients were admitted with COVID‐19, of whom 244 died (4.6%). Diabetes prevalence was 24.8%, but 53.7% of those who died had diabetes. After adjusting for age, sex, ethnicity and other comorbidities, diabetes was associated with death (OR 1.70 [95% CI 1.23, 2.34]) and admission to the intensive care unit more than 3 days after initial admission (OR 1.78 [95% CI 1.17, 2.70]). Assuming causality, the population attributable fraction for type 2 diabetes in COVID‐19 death was 19.6% (95% CI 10.8, 35.6). Conclusion Type 2 diabetes is a strong risk factor for COVID‐19 death in the Middle East. Given the high prevalence of type 2 diabetes in the Middle East, as well as many Western countries, the public health implications are considerable.