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Measurement and hemodialysis effect of complex relative permittivity for blood of kidney patients using open‐ended coaxial measurement probe
Author(s) -
Takeda Akira,
Takata Kazuyuki,
Nagao Hirotomo,
Wang Jianqing,
Fujiwara Osamu
Publication year - 2012
Publication title -
electronics and communications in japan
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.131
H-Index - 13
eISSN - 1942-9541
pISSN - 1942-9533
DOI - 10.1002/ecj.11421
Subject(s) - hemodialysis , permittivity , relative permittivity , dispersion (optics) , dielectric , dialysis , coaxial , materials science , volume (thermodynamics) , biomedical engineering , analytical chemistry (journal) , mathematics , medicine , optics , chemistry , optoelectronics , surgery , physics , thermodynamics , telecommunications , computer science , chromatography
Before evaluating the quality of hemodialysis from the limited volume of human blood using a commercially available open‐ended coaxial probe, we previously measured the complex relative permittivity of pure water from 200 MHz to 6 GHz with respect to its measured liquid volume, and found that 1.9 ml of water in a beaker with a diameter of 24 mm and a depth of 2 mm gives a variation within ± 0.5% for the real part and ± 7% for the imaginary part. Based on the above finding, we measured the dielectric properties of 2.5 ml whole blood at 25 °C for 10 normal healthy subjects and 9 hemodialysis patients. The measured results on healthy subjects show good agreement with the data reported by Gabriel for human blood at 37 °C, while they provide different dispersion characteristics of straight lines for their Cole–Cole plots. The measured results on the patients give further different dispersion characteristics versus the healthy subjects. In an investigation of the above differences statistically, Student's t ‐test revealed that the permittivity at infinite frequency for the Cole–Cole plots is significantly different with a level of 1% among its averaged values for normal healthy subjects and patients before dialysis. © 2012 Wiley Periodicals, Inc. Electron Comm Jpn, 95(12): 56–61, 2012; Published online in Wiley Online Library ( wileyonlinelibrary.com ). DOI 10.1002/ecj.11421