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The project REBOOT protocol: Evaluating a personalized inhibitory control training as an adjunct to cognitive behavioral therapy for bulimia nervosa and binge‐eating disorder
Author(s) -
Manasse Stephanie M.,
Lampe Elizabeth W.,
Gillikin Lindsay,
PayneReichert Adam,
Zhang Fengqing,
Juarascio Adrienne S.,
Forman Evan M.
Publication year - 2020
Publication title -
international journal of eating disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.785
H-Index - 138
eISSN - 1098-108X
pISSN - 0276-3478
DOI - 10.1002/eat.23225
Subject(s) - bulimia nervosa , binge eating disorder , eating disorders , psychology , inhibitory control , binge eating , cognitive behavioral therapy , cognition , clinical psychology , psychiatry
Abstract Outcomes from cognitive behavioral therapy (CBT) for bulimia nervosa (BN) and binge‐eating disorder (BED) are suboptimal. One potential explanation is that CBT fails to adequately target inhibitory control (i.e., the ability to withhold an automatic response), which is a key maintenance factor for binge eating. Computerized inhibitory control training (ICT) is a promising method for improving inhibitory control but is relatively untested in BN/BED. The present study will evaluate a computer‐based ICT as an adjunct to CBT for BN/BED. Participants with BN ( n = 30) or BED ( n = 30) will be randomized to 12 weeks of either CBT + ICT or CBT + a sham training. Trainings will be completed daily for 4 weeks and weekly for 8 weeks. Primary aims include the following: (a) confirm target engagement (evaluate whether ICT improves inhibitory control), (b) test target validation (evaluate whether improvements in inhibitory control are associated with improvements in binge eating), and (c) evaluate the incremental efficacy of ICT on binge eating. Secondary aims include the following: (a) evaluate ICT feasibility and acceptability and (b) assess the moderating effects of approach tendencies on highly palatable food, dietary restraint, and diagnosis. Data will be used to shape a fully powered clinical trial designed to assess efficacy and dose–response effects of ICT for BN/BED.