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Assessment of HRQoL in patients with eating disorders by the beta‐binomial regression approach
Author(s) -
Arostegui Inmaculada,
Padierna Angel,
Quintana Jose M.
Publication year - 2010
Publication title -
international journal of eating disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.785
H-Index - 138
eISSN - 1098-108X
pISSN - 0276-3478
DOI - 10.1002/eat.20713
Subject(s) - depression (economics) , anxiety , quality of life (healthcare) , multivariate statistics , multivariate analysis , medicine , bayesian multivariate linear regression , regression analysis , clinical psychology , psychology , psychiatry , statistics , nursing , mathematics , machine learning , computer science , economics , macroeconomics
Objective: To study the influence of clinical variables on health‐related quality of life (HRQoL) among women with eating disorder (ED) using beta‐binomial regression (BBR) to analyze scores on the Short‐Form 36 (SF‐36) as dependent variable. Method: Female patients diagnosed with ED completed the SF‐36 at the beginning of the study and after 2 years of treatment. Sociodemographic and clinical information was recorded. For the multivariate analysis, we used BBR models to identify factors that influence SF‐36. Results: Questionnaires were completed by 193 women at baseline and 158 (82%) after 2 years of treatment. Anxiety, depression, and the severity of ED, explained scores in most domains of the SF‐36 at baseline. The main predictor of HRQoL after 2 years of follow‐up was the HRQoL in the same domain at baseline. However, depression, anxiety, and duration of symptoms at baseline also significantly influenced HRQoL after 2 years of treatment in some domains. Higher levels of anxiety or depression, longer duration of symptoms, and poorer SF‐36 scores at baseline were associated with worse HRQoL after 2 years of treatment and follow‐up. Discussion: BBR models provide understandable results for clinicians and can be used in multivariate models with HRQoL dependent variables. © 2009 by Wiley Periodicals, Inc. Int J Eat Disord 2010