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Meta‐analysis of the effectiveness of psychological and pharmacological treatments for binge eating disorder
Author(s) -
Vocks Silja,
TuschenCaffier Brunna,
Pietrowsky Reinhard,
Rustenbach Stephan Jeff,
Kersting Anette,
Herpertz Stephan
Publication year - 2010
Publication title -
international journal of eating disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.785
H-Index - 138
eISSN - 1098-108X
pISSN - 0276-3478
DOI - 10.1002/eat.20696
Subject(s) - binge eating , binge eating disorder , psychological intervention , psychology , weight loss , randomized controlled trial , cognitive therapy , eating disorders , cognitive behavioral therapy , clinical psychology , meta analysis , pharmacotherapy , bulimia nervosa , psychiatry , cognition , medicine , obesity
Objective: The aim of this study was to compute and compare mean effects of various treatments for binge eating disorder. Method: A total of 38 studies with 1973 participants fulfilled the defined inclusion criteria. Effect sizes, odds ratios, and simple rates were integrated in fixed and random (mixed) effects categorical models. Results: From randomized controlled trials, psychotherapy and structured self‐help, both based on cognitive behavioral interventions, were found to have large effects on the reduction of binge eating. Regarding pharmacotherapy, mainly comprising antidepressants, randomized controlled trials revealed medium effects for the reduction of binge eating. Uncontrolled studies on weight‐loss treatments demonstrated moderate reductions of binge eating. Combination treatments did not result in higher effects compared with single‐treatment regimens. Except for weight‐loss treatment, none of the interventions resulted in a considerable weight reduction. Discussion: Psychotherapy and structured self‐help, both based on cognitive‐behavioral interventions, should be recommended as the first‐line treatments. © 2009 by Wiley Periodicals, Inc. Int J Eat Disord 2010