Premium
The duration of severe insulin omission is the factor most closely associated with the microvascular complications of Type 1 diabetic females with clinical eating disorders
Author(s) -
Takii Masato,
Uchigata Yasuko,
Tokunaga Shoji,
Amemiya Naoko,
Kinukawa Naoko,
Nozaki Takehiro,
Iwamoto Yasuhiko,
Kubo Chiharu
Publication year - 2008
Publication title -
international journal of eating disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.785
H-Index - 138
eISSN - 1098-108X
pISSN - 0276-3478
DOI - 10.1002/eat.20498
Subject(s) - eating disorders , bulimia nervosa , anorexia nervosa , retinopathy , nephropathy , odds ratio , medicine , risk factor , diabetes mellitus , binge eating disorder , diabetic retinopathy , type 2 diabetes , type 1 diabetes , logistic regression , insulin , psychology , endocrinology , psychiatry
Abstract Objective: To investigate which features of eating disorders are associated with retinopathy and nephropathy in Type 1 diabetic females with clinical eating disorders. Method: Participants were 109 Type 1 diabetic females with clinical eating disorders diagnosed by the structured clinical interview for DSM‐IV (bulimia nervosa [ n = 70], binge‐eating disorder [ n = 28], anorexia nervosa [ n = 7], and eating disorder not otherwise specified [ n = 4]). Retinopathy and nephropathy were screened and demographic, medical, and eating disorder related factors were investigated. To identify the factors associated with each complication, logistic regression analysis was done. Results: Duration of severe insulin omission and duration of Type 1 diabetes were significantly associated with retinopathy (odds ratios = 1.35 and 1.23, respectively) and nephropathy (odds ratio = 1.35 and 1.21, respectively) in multivariate regression analyses. Conclusion: Of the various problematic behavioral factors related to eating disorders, the duration of severe insulin omission was the factor most closely associated with the retinopathy and nephropathy of Type 1 diabetic females with clinical eating disorders by multivariate analysis. This finding may help patients who deliberately omit insulin become aware of medical risk of insulin omission. © 2007 by Wiley Periodicals, Inc. Int J Eat Disord, 2008