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Genetic epidemiology, endophenotypes, and eating disorder classification
Author(s) -
Bulik Cynthia M,
Hebebrand Johannes,
KeskiRahkonen Anna,
Klump Kelly L.,
ReichbornKjennerud Ted,
Mazzeo Suzanne E.,
Wade Tracey D.
Publication year - 2007
Publication title -
international journal of eating disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.785
H-Index - 138
eISSN - 1098-108X
pISSN - 0276-3478
DOI - 10.1002/eat.20398
Subject(s) - endophenotype , eating disorders , psychology , epidemiology , clinical psychology , identification (biology) , developmental psychology , psychiatry , medicine , biology , cognition , pathology , botany
Objective: To explore how genetic epidemiology has informed the identification of endophenotypes and how endophenotypes may inform future classification of eating disorders. Method: Literature review and synthesis. Results: Although a number of endo‐ and subphenotypes have been suggested for eating disorders, few reach the rigorous definitions developed for candidate endophenotypes. Conclusion: Further study of endophenotypes and subphenotypes for eating disorders may assist with developing a more homogenous classification system that more closely reflects underlying biological mechanisms, and provides a clearer focus for the development of coherent models and treatments. © 2007 by Wiley Periodicals, Inc.