Premium
Metoclopramide and unintended weight gain
Author(s) -
Sansone Randy A.,
Sansone Lori A.
Publication year - 2003
Publication title -
international journal of eating disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.785
H-Index - 138
eISSN - 1098-108X
pISSN - 0276-3478
DOI - 10.1002/eat.10181
Subject(s) - metoclopramide , weight gain , gastric emptying , anorexia nervosa , body weight , etiology , medicine , psychology , anesthesia , eating disorders , stomach , psychiatry , vomiting
Objective This paper describes the case of a 19‐year‐old female with anorexia nervosa (restricting type) who was prescribed metoclopramide (Reglan, Robins, Richmond, VA) for delayed gastric emptying. She subsequently experienced dramatic and unintended weight gain. Results The initial treatment of delayed gastric emptying with metoclopramide did not result in a significant change in body weight. However, an increase in the dose resulted in a 20% increase in the patient's body weight over a 2‐month period. Discussion The risks of weight gain that accompany the administration of metoclopramide are discussed, as well as the postulated etiology and psychological implications for the patient. © 2003 by Wiley Periodicals, Inc. Int J Eat Disord 34: 265–268, 2003.