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Olanzapine treatment of anorexia nervosa: A retrospective study
Author(s) -
Malina Amanda,
Gaskill Jill,
McConaha Claire,
Frank Guido K.,
LaVia Maria,
Scholar Lisa,
Kaye Walter H.
Publication year - 2003
Publication title -
international journal of eating disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.785
H-Index - 138
eISSN - 1098-108X
pISSN - 0276-3478
DOI - 10.1002/eat.10122
Subject(s) - olanzapine , anorexia nervosa , psychology , mood , weight gain , anxiety , psychiatry , eating disorders , clinical psychology , schizophrenia (object oriented programming) , medicine , body weight
Background Recent reports raise the possibility that olanzapine, which commonly causes weight gain in non–eating‐disordered subjects, assisted weight gain and mood during refeeding in anorexia nervosa (AN) patients. Methods Eighteen AN subjects who engaged in open treatment with olanzapine were retrospectively questioned about their response. Results Subjects reported a significant reduction in anxiety, difficulty eating, and core eating disorder symptoms after taking olanzapine. Discussion These data lend support to the possibility that olanzapine may be useful in AN patients. Conclusion A controlled trial is necessary to prove that olanzapine is efficacious. © 2003 by Wiley Periodicals, Inc. Int J Eat Disord 33: 234–237, 2003.