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Links between body mass index, total body fat, cholesterol, high‐density lipoprotein, and insulin sensitivity in patients with obesity related to depression, anger, and anxiety
Author(s) -
LaederachHofmann Kurt,
Kupferschmid Susanne,
Mussgay Lutz
Publication year - 2002
Publication title -
international journal of eating disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.785
H-Index - 138
eISSN - 1098-108X
pISSN - 0276-3478
DOI - 10.1002/eat.10063
Subject(s) - medicine , endocrinology , body mass index , insulin , obesity , psychology
Abstract Objective Define links between psychosocial parameters and metabolic variables in obese females before and after a low‐calorie diet. Method Nine female obese patients (age 36.1 ± 7.1 years, body mass index [BMI] > 30 kg/m 2 ) were investigated before and after a 6‐week low‐calorie diet accompanied by behavior therapy. Blood lipids, insulin sensitivity (Bergman protocol), fat distribution (by dual‐energy X‐ray absorptiometry [DEXA]), as well as psychological parameters such as depression, anger, anxiety, symptom load, and well‐being, were assessed before and after the dieting period. Results The females lost 9.6 ± 2.8 kg ( p < .0001) of body weight, their BMI was reduced by 3.5 ± 0.3 kg/m 2 ( p < .0001), and insulin sensitivity increased from 3.0 ± 1.8 to 4.3 ± 1.5 mg/kg ( p = .05). Their abdominal fat content decreased from 22.3 ± 5.5 to 18.9 ± 4.5 kg ( p < .0001). In parallel, psychological parameters such as irritability ( p < .05) and cognitive control ( p < .0001) increased, whereas feelings of hunger ( p < .05), externality ( p < .05), interpersonal sensitivity ( p < .01), paranoid ideation ( p < .05), psychoticism ( p < .01), and global severity index ( p < .01) decreased. Prospectively, differences in body fat (percent) were correlated to nervousness ( p < .05). Waist‐to‐hip ratio (WHR) differences were significantly correlated to sociability ( p < .05) and inversely to emotional instability ( p < .05), whereas emotional instability was inversely correlated to differences in insulin sensitivity ( p < .01). Discussion Weight reduction may lead to better somatic risk factor control. Women with more nervousness and better sociability at the beginning of a diet period may lose more weight than others. © 2002 by Wiley Periodicals, Inc. Int J Eat Disord 32: 58–71 2002.