Premium
Alterations in anterior–posterior patterning and its accompanying changes along the proximal‐distal axis during the fin‐to‐limb transition
Author(s) -
Tanaka Mikiko
Publication year - 2018
Publication title -
genesis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.093
H-Index - 110
eISSN - 1526-968X
pISSN - 1526-954X
DOI - 10.1002/dvg.23053
Subject(s) - anatomy , fin , biology , basal (medicine) , materials science , insulin , composite material , endocrinology
Summary The evolution from fins to limbs was one of the most successful innovations for vertebrates, allowing them to vastly expand their behaviors and habitats. Fossil records suggest that morphological changes occurred not only along the proximal‐distal axis included appearance of the autopod, but also occurred along the anterior‐posterior axis included reductions in the size and number of basal bones and digits. This review focuses on recent progress in developmental and genetic studies aimed at elucidating the mechanisms underlying alteration of anterior‐posterior patterning and its accompanying changes along the proximal‐distal axis during the fin‐to‐limb transition.