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The evolution of gnathostome development: Insight from chondrichthyan embryology
Author(s) -
Gillis J. Andrew,
Shubin Neil H.
Publication year - 2009
Publication title -
genesis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.093
H-Index - 110
eISSN - 1526-968X
pISSN - 1526-954X
DOI - 10.1002/dvg.20597
Subject(s) - retinoic acid , biology , skate , fgf8 , microbiology and biotechnology , sonic hedgehog , embryo , anatomy , fibroblast growth factor , biochemistry , receptor , fishery , signal transduction , gene
Alcian blue skeletal preparations of wild‐type (front) and retinoic acid‐treated (back) embryos of the little skate, Leucoraja erinacea . As in paired fins, the cartilaginous gill rays of L. erinacea are patterned by a retinoic acid‐regulated Sonic hedghog (Shh)‐Fibroblast growth factor 8 (Fgf8) feedback loop, and exposure to exogenous retinoic acid induces ectopic Shh expression and mirror‐image gill ray duplications. (Cover design by Kalliopi Monoyios and Randy Dahn). See the review by Gillis and Shubin in this issue.