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Macrophages in the embryo and beyond: Much more than just giant phagocytes
Author(s) -
Ovchinnikov Dmitry A.
Publication year - 2008
Publication title -
genesis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.093
H-Index - 110
eISSN - 1526-968X
pISSN - 1526-954X
DOI - 10.1002/dvg.20495
Subject(s) - embryo , cyan , embryonic stem cell , biology , transgene , microbiology and biotechnology , genetically modified mouse , macrophage , embryogenesis , virology , genetics , in vitro , gene , art , visual arts
Macrophages in a “MacBlue” mouse embryo at 12 days post coitus, visualized by the expression of enhanced cyan fluorescent protein (ECFP) from a bi‐partite ( Csf1r‐Gal4/UAS‐ECFP ) transgene. Macrophages are interspersed throughout the embryo, with the highest concentration in the embryonic liver; they are also abundant around the developing heart, brain and eyes. See the review by Ovchinnikov in this issue.