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Real time monitoring of BMP Smads transcriptional activity during mouse development
Author(s) -
Monteiro Rui M.,
de Sousa Lopes Susana M. Chuva,
Bialecka Monika,
de Boer Sophie,
Zwijsen An,
Mummery Christine L.
Publication year - 2008
Publication title -
genesis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.093
H-Index - 110
eISSN - 1526-968X
pISSN - 1526-954X
DOI - 10.1002/dvg.20493
Subject(s) - green fluorescent protein , bone morphogenetic protein , smad , bone morphogenetic protein 7 , immunofluorescence , transgene , bone morphogenetic protein 2 , microbiology and biotechnology , biology , genetically modified mouse , transforming growth factor , gene , immunology , genetics , antibody , in vitro
Sagittal section of a 5‐day‐old mouse kidney expressing a bone morphogenetic protein‐response element:green fluorescent protein (BRE:gfp) transgene. GFP expression detected by immunofluorescence (green) reveals BMP Smad transcriptional activity in the glumeruli and adjacent collecting tubules. See the paper by Monteiro et al ., in this issue. (Image provided by Monika Bialecka).