Premium
Hyperactive BMP signaling induced by ALK2 R206H requires type II receptor function in a Drosophila model for classic fibrodysplasia ossificans progressiva
Author(s) -
Le Viet Q.,
Wharton Kristi A.
Publication year - 2012
Publication title -
developmental dynamics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.634
H-Index - 141
eISSN - 1097-0177
pISSN - 1058-8388
DOI - 10.1002/dvdy.23708
Subject(s) - fibrodysplasia ossificans progressiva , biology , bone morphogenetic protein , drosophila (subgenus) , myositis ossificans , function (biology) , microbiology and biotechnology , anatomy , cancer research , genetics , pathology , gene , medicine , heterotopic ossification
Overexpression of human GATA4 in the Drosophila eyes through the GMR‐GAL4 driver. All flies show narrow eyes. The original photograph has been duplicated for esthetic purposes to create 6 panels. From Amodio et al., Developmental Dynamics 241:205‐213, 2012.