Recent advances in understanding the molecular mechanisms regulating  C. elegans  transcription | Zendy

Gaudet Jeb | Zendy; McGhee James D. | Zendy

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Recent advances in understanding the molecular mechanisms regulating C. elegans transcription

Author(s) -

Gaudet Jeb,

McGhee James D.

Publication year - 2010

Publication title -

developmental dynamics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.634

H-Index - 141

eISSN - 1097-0177

pISSN - 1058-8388

DOI - 10.1002/dvdy.22246

Subject(s) - biology , caenorhabditis elegans , transcription factor , histone , transcription (linguistics) , chromatin , nucleosome , cell fate determination , promoter , microbiology and biotechnology , genetics , general transcription factor , computational biology , gene , gene expression , linguistics , philosophy

We review recent studies that have advanced our understanding of the molecular mechanisms regulating transcription in the nematode C. elegans . Topics covered include: (i) general properties of C. elegans promoters; (ii) transcription factors and transcription factor combinations involved in cell fate specification and cell differentiation; (iii) new roles for general transcription factors; (iv) nucleosome positioning in C. elegans “chromatin”; and (v) some characteristics of histone variants and histone modifications and their possible roles in controlling C. elegans transcription. Developmental Dynamics 239:1388–1404, 2010. © 2010 Wiley‐Liss, Inc.

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