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Patterns of muscular strain in the embryonic heart wall
Author(s) -
Damon Brooke J.,
Rémond Mathieu,
Bigelow Michael R.,
Trusk Thomas C.,
Xie Wenjie,
Perucchio Renato,
Sedmera David,
Denslow Stewart,
Thompson Robert P.
Publication year - 2009
Publication title -
developmental dynamics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.634
H-Index - 141
eISSN - 1097-0177
pISSN - 1058-8388
DOI - 10.1002/dvdy.22053
Subject(s) - anatomy , biology , ventricle , apex (geometry) , embryonic heart , myocyte , propidium iodide , biophysics , embryonic stem cell , microbiology and biotechnology , medicine , apoptosis , biochemistry , programmed cell death , gene
Abstract HH Stage 22 chick heart inflated ex ovo with perfusate containing propidium iodide (red) and 3000 MW dextran (green), viewed here in left sagittal plane by confocal microscopy of acrylamide slab sections. Stretch‐sensitive membrane leaks were conspicuous along subendocardial trabeculae near the apex of the looped ventricle (bottom) and along inner wall of AV canal (inset), indicating peak strain of inner wall myocytes as modeled and measured by Damon et al., Developmental Dynamics 238:1535–1546.