Regulation of Wnt/β‐catenin signaling by protein kinases | Zendy

Verheyen Esther M. | Zendy; Gottardi Cara J. | Zendy

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Regulation of Wnt/β‐catenin signaling by protein kinases

Author(s) -

Verheyen Esther M.,

Gottardi Cara J.

Publication year - 2010

Publication title -

developmental dynamics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.634

H-Index - 141

eISSN - 1097-0177

pISSN - 1058-8388

DOI - 10.1002/dvdy.22019

Subject(s) - wnt signaling pathway , biology , kinase , microbiology and biotechnology , signal transduction , catenin , protein serine threonine kinases , protein kinase a

The Wnt/β‐catenin signaling pathway plays essential roles during development and adult tissue homeostasis. Inappropriate activation of the pathway can result in a variety of malignancies. Protein kinases have emerged as key regulators at multiple steps of the Wnt pathway. In this review, we present a synthesis covering the latest information on how Wnt signaling is regulated by diverse protein kinases. Developmental Dynamics 239:34–44, 2010. © 2009 Wiley‐Liss, Inc.

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