VEGF‐mediated fusion in the generation of uniluminal vascular spheroids | Zendy

Gentile Carmine | Zendy; Fleming Paul A. | Zendy; Mironov Vladimir | Zendy; Argraves Kelley M. | Zendy; Argraves W. Scott | Zendy; Drake Christopher J. | Zendy

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VEGF‐mediated fusion in the generation of uniluminal vascular spheroids

Author(s) -

Gentile Carmine,

Fleming Paul A.,

Mironov Vladimir,

Argraves Kelley M.,

Argraves W. Scott,

Drake Christopher J.

Publication year - 2008

Publication title -

developmental dynamics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.634

H-Index - 141

eISSN - 1097-0177

pISSN - 1058-8388

DOI - 10.1002/dvdy.21825

Subject(s) - spheroid , biology , vegf receptors , fusion , microbiology and biotechnology , biophysics , anatomy , cancer research , biochemistry , in vitro , linguistics , philosophy

VEGF‐mediated vascular fusion in the generation of uniluminal spheroids. Luminized vascular networks present in mouse allantoic‐derived tissue spheroids (upper image) fuse when treated with VEGF to form a single central vessel (lower image). Spheroids were immunolabeled with antibodies to PECAM‐1 (green) and SMαA (red). See Gentile et al., Developmental Dynamics 237:2918–2925. Developmental Dynamics 237:2918–2925, 2008. © 2008 Wiley‐Liss, Inc.

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