Pushing the envelope: Developmental regulation by the nuclear lamina
Author(s) -
Kiefer Julie C.
Publication year - 2008
Publication title -
developmental dynamics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.634
H-Index - 141
eISSN - 1097-0177
pISSN - 1058-8388
DOI - 10.1002/dvdy.21523
Subject(s) - nuclear lamina , biology , lamina , envelope (radar) , microbiology and biotechnology , lamin , realization (probability) , nuclear protein , evolutionary biology , gene , computational biology , genetics , anatomy , transcription factor , nucleus , engineering , telecommunications , radar , statistics , mathematics
Abstract A surprising realization in recent years was that proteins of the nuclear lamina directly regulate gene expression and cell differentiation. Presented here are examples that highlight the diverse roles these proteins can inhabit. Accompanying the primer is a discussion of current topics in the field with nuclear lamina experts Colin Stewart, Ph.D., and Yosef Gruenbaum, Ph.D. Developmental Dynamics 237:1526‐1533, 2008. © 2008 Wiley‐Liss, Inc.