Premium
The JAK/STAT pathway regulates proximo‐distal patterning in Drosophila
Author(s) -
AyalaCamargo Aidee,
Ekas Laura A.,
Flaherty Maria Sol,
Baeg GyeongHun,
Bach Erika A.
Publication year - 2007
Publication title -
developmental dynamics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.634
H-Index - 141
eISSN - 1097-0177
pISSN - 1058-8388
DOI - 10.1002/dvdy.21348
Subject(s) - decapentaplegic , biology , psychological repression , drosophila (subgenus) , microbiology and biotechnology , enhancer , imaginal disc , drosophila melanogaster , anatomy , genetics , gene , gene expression
Abstract unpaired , wingless , and decapentaplegic have independent expression domains. unpaired ( upd ) (green), wingless (Wg) (red) and decapentaplegic ( dpp ) (blue) do not overlap in a Drosophila third instar antennal disc. In this issue, Ayala‐Camargo et al. show that these factors mutually repress each other's expression and that this repression is critical for the formation of a single proximo‐distal axis per leg or antenna. upd‐Gal4 , UAS‐gfp enhancer trap (green); Wg protein (red) and dpp‐lacZ (anti Beta‐galactosidase) (blue). Anterior is to the left and dorsal is up. See Ayala‐Camargo et al., Developmental Dynamics 236:2721‐2730. © 2007 Wiley‐Liss, Inc.