Premium
Global patterning of the vertebrate mesoderm
Author(s) -
Winslow Benjamin Britton,
TakimotoKimura Ryoko,
Burke Ann Campbell
Publication year - 2007
Publication title -
developmental dynamics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.634
H-Index - 141
eISSN - 1097-0177
pISSN - 1058-8388
DOI - 10.1002/dvdy.21254
Subject(s) - vertebrate , biology , mesoderm , evolutionary biology , anatomy , appendicular skeleton , postcrania , evolutionary developmental biology , paraxial mesoderm , axial skeleton , lateral plate mesoderm , nodal , computational biology , genetics , paleontology , gene , embryonic stem cell , taxon
We describe recent advances in the understanding of patterning in the vertebrate post‐cranial mesoderm. Specifically, we discuss the integration of local information into global level information that results in the overall coordination along the anterioposterior axis. Experiments related to the integration of the axial and appendicular musculoskeletal systems are considered, and examples of genetic interactions between these systems are outlined. We emphasize the utility of the terms primaxial and abaxial as an aid to understanding development of the vertebrate musculoskeletal system, and hypothesize that the lateral somitic frontier is a catalyst for evolutionary change. Developmental Dynamics 236:2371–2381, 2007. © 2007 Wiley‐Liss, Inc.