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Expression of Wise in chick embryos
Author(s) -
Shigetani Y.,
Itasaki N.
Publication year - 2007
Publication title -
developmental dynamics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.634
H-Index - 141
eISSN - 1097-0177
pISSN - 1058-8388
DOI - 10.1002/dvdy.21234
Subject(s) - ectoderm , biology , neurula , morphogenesis , embryo , microbiology and biotechnology , in situ hybridization , wnt signaling pathway , anatomy , apical ectodermal ridge , endoderm , embryogenesis , limb development , gene expression , gastrulation , genetics , gene , cellular differentiation , signal transduction
We have performed in situ hybridization to study the expression of Wise in early chick embryos. Wise expression is first detectable in the ectoderm at posterior levels of late neurula. As development proceeds, Wise expression is seen in specific patterns in the ectoderm of the trunk region, pharyngeal arches, limb buds, and feather buds. In addition to these areas, particular cartilages such as the ones in the maxillary process and limbs start to express Wise at the late pharyngula stage, and the expression in these cartilages becomes stronger than that in epidermal components at later stages. Importantly, Wise is expressed in regions where other signaling molecules such as Wnt, Bmp, and Shh are known to function in morphogenesis and differentiation. Direct comparisons of the expression of Wise and these genes are also demonstrated. Developmental Dynamics 236:2277–2284, 2007. Published 2007 Wiley‐Liss, Inc.