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Back to basics: Sox genes
Author(s) -
Kiefer Julie C.
Publication year - 2007
Publication title -
developmental dynamics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.634
H-Index - 141
eISSN - 1097-0177
pISSN - 1058-8388
DOI - 10.1002/dvdy.21218
Subject(s) - biology , neural crest , neurogenesis , gene , cell fate determination , neural development , neuroscience , computational biology , genetics , microbiology and biotechnology , evolutionary biology , transcription factor
Sox genes are indispensable for multiple aspects of development. This primer briefly describes shared properties of the Sox gene family, and five well‐characterized examples of vertebrate developmental mechanisms governed by Sox gene subgroups: testis development, central nervous system neurogenesis, oligodendrocyte development, chondrogenesis, and neural crest cell development. Also featured is an interview about current issues in the field with experts Jonas Muhr, Ph.D. and Robert Kelsh, Ph.D. Developmental Dynamics 236:2356–2366, 2007. © 2007 Wiley‐Liss, Inc.