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Segmental expression of the T‐box transcription factor, Tbx2 , during early somitogenesis
Author(s) -
Harrelson Zachary,
Papaioannou Virginia E.
Publication year - 2006
Publication title -
developmental dynamics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.634
H-Index - 141
eISSN - 1097-0177
pISSN - 1058-8388
DOI - 10.1002/dvdy.20928
Subject(s) - somitogenesis , biology , transcription factor , somite , microbiology and biotechnology , embryo , anatomy , gene , genetics , embryogenesis
Tbx2 belongs to the T‐box transcription factor gene family and is expressed in a variety of tissues and structures throughout development, although not all expression domains have been thoroughly described. Two areas of segmented expression along the rostral‐caudal axis of E10.5–11.5 embryos were identified as inter‐somitic vessels and dorsal root ganglia. In addition, Tbx2 expression is observed during somitogenesis beginning at E9.5, both in the posterior half of prospective somites and in a progressively restricted pattern in recently formed somites. Developmental Dynamics 235:3080–3084, 2006. © 2006 Wiley‐Liss, Inc.