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Proneural factors and neurogenesis
Author(s) -
Kiefer Julie C.
Publication year - 2005
Publication title -
developmental dynamics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.634
H-Index - 141
eISSN - 1097-0177
pISSN - 1058-8388
DOI - 10.1002/dvdy.20522
Subject(s) - neurogenesis , biology , neural stem cell , proneural genes , neuroscience , dialog box , neural development , progenitor cell , microbiology and biotechnology , genetics , stem cell , gene , computer science , world wide web
The role of proneural factors in specifying neuronal progenitors and in promoting neuronal differentiation is conserved from Drosophila to vertebrates. This primer discusses the basic functions of proneural factors in neurogenesis, mechanisms of proneural factor function, and models for how proneural factors generate neuronal subtypes. The primer also features a dialog about current topics and future directions in the field between two experts in neurogenesis: Andrew Jarman, Ph.D., and Jane Johnson, Ph.D. Developmental Dynamics 234:808–813, 2005. © 2005 Wiley‐Liss, Inc.