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Genome‐wide identification of female‐enriched genes in zebrafish
Author(s) -
Wen Chaoming,
Zhang Zhenhai,
Ma Weiping,
Xu Min,
Wen Zilong,
Peng Jinrong
Publication year - 2005
Publication title -
developmental dynamics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.634
H-Index - 141
eISSN - 1097-0177
pISSN - 1058-8388
DOI - 10.1002/dvdy.20210
Subject(s) - biology , zebrafish , gene , genetics , transcriptome , somatic cell , genome , germline , vertebrate , complementary dna , gene expression
Characteristic differences in morphology, physiology, and behavior between a male and female are correlated to the differential selection of sex‐dependent transcriptomes. By using a cDNA array carrying ∼9,000 zebrafish unique genes, we identified a group of genes whose expression are enriched in the female fish. A subset of these genes have been confirmed and further grouped as egg‐enriched genes, as both somatic‐ and egg‐enriched genes or as somatic‐enriched genes by means of RNA gel blot hybridization. Most importantly, a significant proportion of these genes are either functionally unknown or are novel genes. Thus, future studies of this group of genes will help us greatly to understand more about sex‐determination and sex‐related physiology and behavior. In addition, comparison of zebrafish female‐enriched genes with that in Drosophila , we found that only germline genes are shared between vertebrate and invertebrate, suggesting that the process of oogenesis is highly conserved during the evolution. Developmental Dynamics 232:171–179, 2005. © 2004 Wiley‐Liss, Inc.