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Sphedgehog is expressed by pigment cell precursors during early gastrulation in Strongylocentrotus purpuratus
Author(s) -
Egaña Ana L.,
Ernst Susan G.
Publication year - 2004
Publication title -
developmental dynamics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.634
H-Index - 141
eISSN - 1097-0177
pISSN - 1058-8388
DOI - 10.1002/dvdy.20125
Subject(s) - strongylocentrotus purpuratus , biology , gastrulation , microbiology and biotechnology , sea urchin , zoology , anatomy , embryo , embryogenesis
We have sequenced the Sphedgehog ( Sphh ) gene from the sea urchin Strongylocentrotus purpuratus . Sphh transcripts are detected first at the mesenchyme blastula stage, and they accumulate throughout early embryogenesis. The Sphh protein is produced by precursor pigment cells during early and midgastrulation. NiCl 2 inhibits pigment cell differentiation in sea urchins. Here, we show that, in S. purpuratus , nickel affects a process(es) between 17 and 24 hr of development, corresponding to the time period when Sphh mRNA is first detected. However, nickel treatment does not alter the early expression of Sphh . Developmental Dynamics 231:370–378, 2004. © 2004 Wiley‐Liss, Inc.