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Pax6 is a direct, positively regulated target of the circadian gene Clock
Author(s) -
Morgan Richard
Publication year - 2004
Publication title -
developmental dynamics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.634
H-Index - 141
eISSN - 1097-0177
pISSN - 1058-8388
DOI - 10.1002/dvdy.20097
Subject(s) - biology , pax6 , transcription factor , circadian rhythm , regulator , circadian clock , microbiology and biotechnology , transcription (linguistics) , genetics , gene , oscillating gene , clock , neuroscience , linguistics , philosophy
Clock is a member of a highly conserved transcription control network that underlies the circadian cycle. During early embryogenesis, its expression is developmentally regulated and may be required for the normal development of the head. In this report, the transcription factor Pax6 , a highly conserved regulator of anterior development, is shown to be a direct target of Clock regulation. Developmental Dynamics 230:643–650, 2004. © 2004 Wiley‐Liss, Inc.