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Expression analysis of the Drosophila pipsqueak family members fernández/distal antenna and hernández/distal antenna related
Author(s) -
Suzanne Magali
Publication year - 2004
Publication title -
developmental dynamics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.634
H-Index - 141
eISSN - 1097-0177
pISSN - 1058-8388
DOI - 10.1002/dvdy.20046
Subject(s) - biology , gene , transcription factor , genetics , drosophila melanogaster , microbiology and biotechnology
Abstract The “pipsqueak” family is composed of proteins that contain a pipsqueak motif, a previously characterised DNA binding domain, and thus represents a new family of potential transcription factors. Previous functional characterisation of several Drosophila genes encoding pipsqueak domain‐containing proteins has shown their crucial role in development. Here, I report the embryonic, larval, and pupal expression pattern of two Drosophila genes, fernández/distal antenna and hernández/distal antenna related , which encode protein members of the pipsqueak family with similar pipsqueak motifs. Furthermore, I show that, consistently with their expression pattern, these two genes are required in the nervous system during the embryonic development. Developmental Dynamics 230:361–365, 2004. © 2004 Wiley‐Liss, Inc.