Premium
Do dried blood spots have the potential to support result management processes in routine sports drug testing?—Part 2: Proactive sampling for follow‐up investigations concerning atypical or adverse analytical findings
Author(s) -
Thevis Mario,
Kuuranne Tiia,
Thomas Andreas,
Geyer Hans
Publication year - 2021
Publication title -
drug testing and analysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.065
H-Index - 54
eISSN - 1942-7611
pISSN - 1942-7603
DOI - 10.1002/dta.3011
Subject(s) - dried blood spot , dried blood , context (archaeology) , drug , medicine , intensive care medicine , pharmacology , chemistry , chromatography , biology , paleontology
Capillary blood sampled as dried blood spot (DBS) has shown substantial potential as test matrix in sports drug testing in various different settings, enabling the analysis of numerous different drugs and/or their respective metabolites. In addition to established beneficial aspects of DBS specimens in general (such as the minimally invasive and non‐intrusive nature, and simplified sample transport), a yet unexplored advantage of DBS in the anti‐doping context could be the opportunity of preserving a source of information complementary to routine doping controls performed in urine or venous blood. Whenever follow‐up investigations are warranted or required, frequently collected and stored (but yet not analyzed) DBS samples could be target‐tested for the compound(s) in question, in order to contribute to results management and decision‐making processes.