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Olodaterol and vilanterol detection in sport drug testing
Author(s) -
Chundela Zdenek,
Große Joachim
Publication year - 2015
Publication title -
drug testing and analysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.065
H-Index - 54
eISSN - 1942-7611
pISSN - 1942-7603
DOI - 10.1002/dta.1918
Subject(s) - drug , pharmacology , substance abuse detection , drug detection , medicine , chemistry , chromatography
The possibility of the detection of olodaterol and vilanterol, two novel β 2 ‐agonists, in human urine for the purpose of sport drug testing was investigated. Compounds of interest were analyzed by liquid chromatography‐tandem mass spectrometry (LC‐MS/MS) employing methods commonly used in the World Anti‐Doping Agency (WADA) accredited laboratories. For both substances, the respective parent compound was found to be a suitable target analyte for monitoring therapeutic dose administration. Copyright © 2015 John Wiley & Sons, Ltd.