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Annual banned‐substance review: analytical approaches in human sports drug testing
Author(s) -
Thevis Mario,
Kuuranne Tiia,
Geyer Hans,
Schänzer Wilhelm
Publication year - 2015
Publication title -
drug testing and analysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.065
H-Index - 54
eISSN - 1942-7611
pISSN - 1942-7603
DOI - 10.1002/dta.1769
Subject(s) - agency (philosophy) , identification (biology) , substance abuse detection , risk analysis (engineering) , drug , medicine , computer science , pharmacology , biology , philosophy , botany , epistemology
Within the mosaic display of international anti‐doping efforts, analytical strategies based on up‐to‐date instrumentation as well as most recent information about physiology, pharmacology, metabolism, etc., of prohibited substances and methods of doping are indispensable. The continuous emergence of new chemical entities and the identification of arguably beneficial effects of established or even obsolete drugs on endurance, strength, and regeneration, necessitate frequent and adequate adaptations of sports drug testing procedures. These largely rely on exploiting new technologies, extending the substance coverage of existing test protocols, and generating new insights into metabolism, distribution, and elimination of compounds prohibited by the World Anti‐Doping Agency (WADA). In reference of the content of the 2014 Prohibited List, literature concerning human sports drug testing that was published between October 2013 and September 2014 is summarized and reviewed in this annual banned‐substance review, with particular emphasis on analytical approaches and their contribution to enhanced doping controls. Copyright © 2014 John Wiley & Sons, Ltd.