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A rapid method for profiling samples of illicit heroin
Author(s) -
Zhang Jianxin,
Chen Cunyi
Publication year - 2012
Publication title -
drug testing and analysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.065
H-Index - 54
eISSN - 1942-7611
pISSN - 1942-7603
DOI - 10.1002/dta.1335
Subject(s) - noscapine , heroin , codeine , chromatography , derivatization , morphine , chemistry , pharmacology , medicine , mass spectrometry , alkaloid , drug , stereochemistry
The aim of this investigation was to profile samples of illicit heroin. It involved derivatization and gas chromatographic separation followed by a fully automated data analysis. Six major constituents (acetylcodeine, 6‐monoacetylmorphine, papaverine, noscapine, codeine, and morphine) were tested and analyzed. The square cosine function was used to evaluate correlation values. The method proved to be efficient and reliable providing information on links between illicit heroin samples. Copyright © 2012 John Wiley & Sons, Ltd.