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Electrical transmission: Two structures, same functions?
Author(s) -
Pereda Alberto E.,
Macagno Eduardo
Publication year - 2017
Publication title -
developmental neurobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.716
H-Index - 129
eISSN - 1932-846X
pISSN - 1932-8451
DOI - 10.1002/dneu.22488
Subject(s) - biology , vertebrate , neuroscience , electrical synapses , representation (politics) , function (biology) , neurotransmission , nervous system , transmission (telecommunications) , functional diversity , structure function , evolutionary biology , ecology , computer science , receptor , telecommunications , biochemistry , physics , particle physics , gap junction , politics , gene , microbiology and biotechnology , political science , law , intracellular
Electrical synapses are finding increasing representation and importance in our understanding of signaling in the nervous system. In contrast to chemical synapses, at which molecules are evolutionary conserved, vertebrate and invertebrate electrical synapses represent molecularly different structures that share a common communicating strategy that allows them to serve very similar functions. A better understanding of differences and commonalities regarding the structure, function and regulation of vertebrate and invertebrate electrical synapses will lead to a better understanding of the properties and functional diversity of this modality of synaptic communication. © 2016 Wiley Periodicals, Inc. Develop Neurobiol 77: 517–521, 2017