More than one ring to bind them all: Recent insights into the structure of the axon | Zendy

Gallo Gianluca | Zendy

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More than one ring to bind them all: Recent insights into the structure of the axon

Author(s) -

Gallo Gianluca

Publication year - 2013

Publication title -

developmental neurobiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.716

H-Index - 129

eISSN - 1932-846X

pISSN - 1932-8451

DOI - 10.1002/dneu.22100

Subject(s) - biology , axon , cytoskeleton , actin , neuroscience , axon guidance , actin cytoskeleton , growth cone , protein filament , theme (computing) , regulator , microbiology and biotechnology , genetics , cell , computer science , gene , operating system

This brief review outlines recent developments in the understanding of the ultrastructural organization of the axonal and growth cone actin filament cytoskeleton. A novel form of structural organization has arisen as a regulator of the actin cytoskeleton: ring‐like structures. Rings may represent a conserved functional theme exhibited by diverse molecular systems and have implications for the understanding of the axon in development, maturity, and disease. © 2013 Wiley Periodicals, Inc. Develop Neurobiol 73:799–805, 2013

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