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Building the posterior lateral line system in zebrafish
Author(s) -
Chitnis Ajay B.,
Dalle Nogare Damian,
Matsuda Miho
Publication year - 2012
Publication title -
developmental neurobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.716
H-Index - 129
eISSN - 1932-846X
pISSN - 1932-8451
DOI - 10.1002/dneu.20962
Subject(s) - zebrafish , lateral line , biology , morphogenesis , primordium , neuroscience , line (geometry) , sensory system , regeneration (biology) , anatomy , microbiology and biotechnology , genetics , gene , geometry , mathematics
The posterior lateral line (pLL) in zebrafish has emerged as an excellent system to study how a sensory organ system develops. Here we review recent studies that illustrate how interactions between multiple signaling pathways coordinate cell fate, morphogenesis, and collective migration of cells in the posterior lateral line primordium. These studies also illustrate how the pLL system is contributing much more broadly to our understanding of mechanisms operating during the growth, regeneration, and self‐organization of other organ systems during development and disease. © 2011 Wiley Periodicals, Inc. Develop Neurobiol 72: 234–255, 2012