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Cell cycle regulation and interneuron production
Author(s) -
Ross M. Elizabeth
Publication year - 2010
Publication title -
developmental neurobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.716
H-Index - 129
eISSN - 1932-846X
pISSN - 1932-8451
DOI - 10.1002/dneu.20823
Subject(s) - biology , interneuron , neuroscience , production (economics) , inhibitory postsynaptic potential , economics , macroeconomics
The regulation of progenitor proliferation in developing brain in has been extensively studied in the cerebral cortex, but relatively little is known about progenitor divisions in ventral germinal zones. Recent observations pertinent to interneuron genesis in the ventral forebrain, especially in the medial ganglionic eminence, indicate similarities to cerebral cortical neurogenesis and hint at some interesting differences between ventral and dorsal telencephalon progenitors. Proliferation within the ganglionic eminences is discussed from the vantage point of neural precursor cell cycles, especially G1‐phase, and current models of neurogenic divisions in cortex that may apply to ventral forebrain as well. © 2010 Wiley Periodicals, Inc. Develop Neurobiol 71: 2–9, 2011