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Using imaging and genetics in zebrafish to study developing spinal circuits in vivo
Author(s) -
McLean David L.,
Fetcho Joseph R.
Publication year - 2008
Publication title -
developmental neurobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.716
H-Index - 129
eISSN - 1932-846X
pISSN - 1932-8451
DOI - 10.1002/dneu.20617
Subject(s) - zebrafish , danio , biology , biological neural network , neuroscience , electronic circuit , neuronal circuits , spinal cord , genetics , gene , physics , quantum mechanics
Imaging and molecular approaches are perfectly suited to young, transparent zebrafish ( Danio rerio ), where they have allowed novel functional studies of neural circuits and their links to behavior. Here, we review cutting‐edge optical and genetic techniques used to dissect neural circuits in vivo and discuss their application to future studies of developing spinal circuits using living zebrafish. We anticipate that these experiments will reveal general principles governing the assembly of neural circuits that control movements. © 2008 Wiley Periodicals, Inc. Develop Neurobiol, 2008