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MR imaging methods for assessing fetal brain development
Author(s) -
Rutherford Mary,
Jiang Shuzhou,
Allsop Joanna,
Perkins Lucinda,
Srinivasan Latha,
Hayat Tayyib,
Kumar Sailesh,
Hajnal Jo
Publication year - 2008
Publication title -
developmental neurobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.716
H-Index - 129
eISSN - 1932-846X
pISSN - 1932-8451
DOI - 10.1002/dneu.20614
Subject(s) - neuroscience , biology , fetus , magnetic resonance imaging , brain development , neuroimaging , pregnancy , medicine , radiology , genetics
Fetal magnetic resonance imaging provides an ideal tool for investigating growth and development of the brain in vivo . Current imaging methods have been hampered by fetal motion but recent advances in image acquisition can produce high signal to noise, high resolution 3‐dimensional datasets suitable for objective quantification by state of the art post acquisition computer programs. Continuing development of imaging techniques will allow a unique insight into the developing brain, more specifically process of cell migration, axonal pathway formation, and cortical maturation. Accurate quantification of these developmental processes in the normal fetus will allow us to identify subtle deviations from normal during the second and third trimester of pregnancy either in the compromised fetus or in infants born prematurely. © 2008 Wiley Periodicals, Inc. Develop Neurobiol, 2008