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Association of adiposity with diabetes: A national research among Chinese adults
Author(s) -
Fu Wenning,
Wang Chao,
Zou Li,
Jiang Heng,
Miller Mia,
Gan Yong,
Cao Shiyi,
Xu Hongbin,
Mao Jing,
Yan Shijiao,
Yue Wei,
Yan Feng,
Tian Qingfeng,
Lu Zuxun
Publication year - 2021
Publication title -
diabetes/metabolism research and reviews
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.307
H-Index - 110
eISSN - 1520-7560
pISSN - 1520-7552
DOI - 10.1002/dmrr.3380
Subject(s) - waist , medicine , body mass index , diabetes mellitus , obesity , odds ratio , confidence interval , demography , waist to height ratio , body shape index , risk factor , endocrinology , classification of obesity , fat mass , sociology
Background Adiposity is an established risk factor for diabetes. The different measurements of adiposity for predicting diabetes have been compared in recent studies in Western countries. However, similar researches among Chinese adults are limited. Methods Data were collected from a national survey conducted during September 2014 and May 2015 Among Chinese adults aged 40 years and older across 30 China's provinces. Multilevel model analysis was performed to examine the impacts of different obesity indices [body mass index (BMI), waist circumference (WC), lipid accumulation product index (LAP), visceral adiposity index (VAI), and body adiposity index (BAI)] on the risk of diabetes. Results A total of 162 880 participants were included in this study. Of them, 54.47% were female. With an increase in BMI, WC, LAP, VAI, and BAI, the prevalence of diabetes significantly grew ( P < 0.001). The multilevel model analysis showed that WC has the strongest impact on diabetes prevalence, while BAI was the weakest. For one SD increment in BMI, WC, LAP, VAI, and BAI, the prevalence of diabetes increased by 27.0% ( Odds Ratio (OR) = 1.270, 95% Confidence interval (CI) = 1.251–1.289), 37.4% ( OR = 1.374, 95% CI = 1.346–1.401), 28.1% ( OR = 1.281, 95% CI = 1.266–1.297), 22.0% ( OR = 1.220, 95% CI = 1.204–1.236), and 17.4% ( OR = 1.174, 95% CI = 1.151–1.192), respectively. Conclusion Obesity indicators of BMI, WC, LAP, VAI, and BAI have significant positive relationships with the risk of diabetes. WC has the strongest impact on diabetes, while BAI has the weakest.