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The importance of nonstop treatment after delivery for pregnant women with type 2 diabetes
Author(s) -
Omori Yasue,
Yanagisawa Keiko,
Sato Asako,
Uchigata Yasuko
Publication year - 2017
Publication title -
diabetes/metabolism research and reviews
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.307
H-Index - 110
eISSN - 1520-7560
pISSN - 1520-7552
DOI - 10.1002/dmrr.2860
Subject(s) - medicine , albuminuria , glycemic , diabetes mellitus , type 2 diabetes , nonstop , retinopathy , type 1 diabetes , pregnancy , diabetic retinopathy , pediatrics , obstetrics , surgery , endocrinology , biology , computer science , genetics , operating system
Background There are no reports of very long follow‐up studies of pregnant women with type 2 diabetes after delivery. Here we describe cases of Japanese women whom we treated for 20 to 50 years after deliveries to investigate the relationship between blood glucose control and diabetic complications. Methods In Japan, the prevalence of type 1 diabetes is very low, and we have very few long‐term follow‐up cases with type 1 diabetes. Therefore, we chose to describe subjects with type 2 diabetes only. We present data on a total of 80 deliveries, 68 cases, treated by one of us (Y.O.) for more than a 50‐year period. They are divided into 4 groups based on duration of treatment after delivery: more than 50 years (1 delivery, 1 patient), 40 to 49 years (13 deliveries, 11 patients), 30 to 39 years (19 deliveries, 16 patients), and 20 to 29 years (47 deliveries, 40 patients). Their present average ages in these 4 groups are 77, 72.4, 65.9, and 55.5 years, respectively. Their average HbA1c levels at last visit, in May 2014, are 8.2%, 7.6%.,7.2%, and 8.3%, respectively. Results Despite elevated HbA1c levels, they had relatively few complications: 40% (no retinopathy), 43.8% (simple retinopathy), and 12.5% (treated with photocoagulation); 67.5% (no albuminuria), 26.3% (albuminuria), and 6.3% (treated with renal transplantation or hemodialysis). Therefore, even if glycemic control is not ideal, nonstop treatment of Japanese women for type 2 diabetes after deliveries is effective to prevent diabetic complications. Conclusions Long‐term attention to care of diabetes after pregnancy may be preventive of diabetic complications in other populations as well.