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Management status and its predictive factors in patients with type 2 diabetes in China: A Nationwide Multicenter Study
Author(s) -
Liu Lin,
Lou Qingqing,
Guo Xiaohui,
Yuan Li,
Shen Li,
Sun Zilin,
Zhao Fang,
Dai Xia,
Huang Jin,
Yang Huiying,
Mordes John P.
Publication year - 2015
Publication title -
diabetes/metabolism research and reviews
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.307
H-Index - 110
eISSN - 1520-7560
pISSN - 1520-7552
DOI - 10.1002/dmrr.2757
Subject(s) - medicine , dyslipidemia , body mass index , glycated hemoglobin , diabetes mellitus , type 2 diabetes , blood pressure , logistic regression , type 2 diabetes mellitus , population , obesity , endocrinology , environmental health
Abstract Background The prevalence of type 2 diabetes in China is increasing rapidly. Appropriate management of glycemia, blood pressure and dyslipidemia in this population is a major public health concern. Objective The aim of this study was to assess metabolic control including glycated hemoglobin A 1c (HbA 1c ), blood pressure (BP) and low density lipoprotein cholesterol (LDL‐c), in a large sample of patients with type 2 diabetes in China and to identify factors that correlated with the achievement of HbA1c, BP and LDL‐c goals (ABCs). Method A nationwide survey was conducted in 50 medical centres across China from April to July of 2010. Baseline information on demographics, medical history, HbA 1c , BP and LDL‐c levels were measured in 5961 patients with type 2 diabetes. Results Mean age, body mass index (BMI) and HbA 1c were 59.5 ± 1.3 years, 24.5 ± 4.1 kg/m 2 and 8.3 ± 2.2%, respectively. With respect to generally accepted ABC treatment goals, 35.2% of participants had HbA 1c <7%; 35.5% had BP < 140/80 mmHg, and 45.1% had LDL‐c < 100 mg/dl. The proportion of patients who met all three targets was only 5.4%. Logistic regression revealed that smoking ( P =0.000), higher BMI ( P =0.001) and insulin use ( P =0.000) were statistically significant predictors of failing to meet ABC targets. Conclusion The percentage of Chinese patients with type 2 diabetes who met recommended targets for HbA 1c , BP and LDL‐c in 2010 was low. Smoking, higher BMI and insulin use were the strongest determinants of failing to meet ABC targets. Copyright © 2015 John Wiley & Sons, Ltd.