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Bariatric surgery: beta cells in type 2 diabetes remission
Author(s) -
Su Yinjie,
Zhao Yanling,
Zhang Chaojun
Publication year - 2016
Publication title -
diabetes/metabolism research and reviews
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.307
H-Index - 110
eISSN - 1520-7560
pISSN - 1520-7552
DOI - 10.1002/dmrr.2663
Subject(s) - type 2 diabetes , medicine , beta (programming language) , diabetes mellitus , regeneration (biology) , beta cell , surgery , endocrinology , biology , microbiology and biotechnology , computer science , islet , programming language
Summary Bariatric surgery is a new emerging treatment that demonstrates a favourable effect on type 2 diabetes, although its underlying mechanisms still remain unknown. After receiving bariatric surgery, beta cells undergo the process of rebirth, which involves apoptosis evasion, regeneration and improved beta‐cell function. Therefore, further studies are necessary to elucidate how bariatric surgery can resolve type 2 diabetes. Here, our review focuses mainly on beta cells, the insulin‐generating cells, whose biological features change dramatically after bariatric surgery. Copyright © 2015 John Wiley & Sons, Ltd.