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Diabetes, dysglycemia and cognitive dysfunction
Author(s) -
CukiermanYaffe Tali
Publication year - 2014
Publication title -
diabetes/metabolism research and reviews
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.307
H-Index - 110
eISSN - 1520-7560
pISSN - 1520-7552
DOI - 10.1002/dmrr.2507
Subject(s) - dementia , cognition , diabetes mellitus , cognitive decline , disease , medicine , psychology , type 2 diabetes , gerontology , intensive care medicine , psychiatry , endocrinology
Summary Evidence from the last decade supports the hypothesis that diabetes may be viewed as a disease of accelerated cognitive ageing. It is a risk factor for the development of dementia, for an accelerated rate of cognitive decline and for cognitive dysfunction. Thus, ‘diabetes‐related cognitive dysfunction’ may be viewed as another long‐term complication of diabetes. This article will review the evidence supporting this hypothesis and will elaborate on the implications for patient care, as well as discuss potential treatment options and their limitation. The final section reviews possible mechanistic explanations. Copyright © 2013 John Wiley & Sons, Ltd.