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Auditory brainstem response in sheep. Part I: Fetal development
Author(s) -
Pierson Linda L.,
Gerhardt Kenneth J.,
Griffiths Scott K.,
Abrams Robert M.
Publication year - 1995
Publication title -
developmental psychobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.055
H-Index - 93
eISSN - 1098-2302
pISSN - 0012-1630
DOI - 10.1002/dev.420280505
Subject(s) - auditory brainstem response , brainstem , in utero , gestation , fetus , audiology , tone burst , gestational age , medicine , biology , pregnancy , hearing loss , genetics
The Auditory Brainstem Response (ABR) was recorded from fetal sheep in utero between gestational ages of 111 days and 136 days (Normal gestation is 145 days). The ABR was detected at 111 days gestation (dGA) and morphology of the waveform improved rapidly from 116 to 123 dGA. At 123 dGA, the four vertex‐positive peaks were similar to those observed in adult ewes. Thresholds of the ABR to clicks and tone bursts improved rapidly between 111 and 123 dGA. From 123 to 136 dGA, ABR thresholds continued to improve, but at a much slower rate. Latencies for the peaks also decreased during development from 111 to 136 days, with latencies for Waves III and IV showing a greater decrease than latencies for Waves I and II. © 1995 John Wiley & Sons, Inc.